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Softgel capsule Benefits in Natural Health and pharmaceutical products

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Soft Gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds. In addition, soft gels offer many other key advantages and therapeutic benefits:

Ease of Swallowing

• Convenience

• Acceptability

Dosage Accuracy

• Uniformity and precision dosageSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption.

Adaptability

• LiquidSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.

• Semi-solids

• Suspension

• Emulsion

Product Security

• Dosage and formulation are tamper-resisSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorptiontant (a punctured or tampered softgels will leak or become discoloured)

• Protection against counterfeit

Product StabilitySoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption

• Sealed container

• Protection from light for photosensitive formulations

• Masking of objectionable odors and tastes

• Protects drug from oxidation and degradation

Market Differentiation

• Size, shape and colour customizationSoftgel capsule Benefits in natural health and pharmaceutical products

• Soft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of botSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.h insoluble and lipid-soluble compounds.Imprintability of capsulesSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption

Softgel technology

Softgel benefits of Biological and marketing advantage:

• Better protection of active ingredients—hermetically sealed dosage form protects drug from oxidation and degradation.

• Improved absorption and bioavailability— any formulations in softgel can enhance bioavailability or produce a quicker onset ofSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds. action.

• Marketplace differentiation—a nearly endless array of shapes, sizes and shell colors helps your product stand out from branded or generic competitors.

• Consumer preference—results of studies done through the years show that consumers expressed their preference for softgels in terms of ease of swallowing, perceived speed of delivery, lack of unpleasant odor or taste, and modern appearance.

• Tamper evidence—a punctured or otherwise tampered softgel will leak or become discolored, indicating a potential problem.

Formulation characteristics:

• Self-emulsifying/microemulsion vehicle systems

• Liquid (solution or suspension) fillsSoftgel Vitamin Manufacturing

• Wide range of softgel-compatible vehicles (hydrophilic/lipophilic)

• Virtually unlimited selection of shapes, sizes and colors

• Unique formulations leading to patentable line extensions

• New technologies, including innovative shell forms and manufacturing techniques

Key advantages:

• Enhanced bioavailability

• Minimizes patient-to-patient variability

• Possible lowered drug dosing

• Excellent dose uniformity

• Obvious evidence of tampering

• Ability to solubilize a wide range of active ingredientSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.s

• Maximizes drug loading

• Extensive product differentiation possibilities

• Enhanced life-cycle managementSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.

By Nutralab Canada Ltd. ( www.nutralab.ca)

About the Author

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For more information about Softgel Vitamin Manufacturing please visit www.nutralab.ca

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